Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing
- Conditions
- Pacemaker Implantation for Sinus Node Disease
- Interventions
- Other: pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function
- Registration Number
- NCT01803217
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Brief Summary
Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators.
The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular hysteresis function versus mode switch to atrial pacing) to reduce right ventricular pacing.
- Detailed Description
Comparison of the effect of an atrioventricular hysteresis function with a mode switch to atrial pacing on the right ventricular pacing percentage in a multi-centre, prospective, randomized, single blinded, cross-over study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 70
Indication for the implantation of a dual-chamber pacemaker
Persistent or permanent atrial tachyarrhythmias atrioventricular block 2nd or 3rd degree indication or the implantation of an defibrillator
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description mode switch to atrial pacing pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function - atrioventricular hysteresis function pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function -
- Primary Outcome Measures
Name Time Method Right ventricular pacing percentage 3 months
- Secondary Outcome Measures
Name Time Method BNP levels 3 months
Trial Locations
- Locations (3)
Krankenhaus Peißenberg
🇩🇪Peißenberg, Bayern, Germany
Klinikum Bamberg
🇩🇪Bamberg, Bayern, Germany
Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen
🇩🇪München, Bayern, Germany