Revealing individual neural underpinnings of anxiety in healthy subjects

Recruiting

• Conditions: anxiety; 10002861

• Registration Number: NL-OMON44325
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

healthy volunteers (18-50 years)
fMRI compartibility

Exclusion Criteria

History of or current neurological or psychiatric treatment
History of or current brain surgery or epilepsy
Pregnancy
Metal parts in the upper body, implants, medical devices or medicinal plasters
Claustrophobia

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In the fMR session three paradigms will be tested to determine the neural<br /><br>phenotype:<br /><br>- prefrontal regulation task<br /><br>- salience processing task<br /><br>- face processing task</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>questionnaires:<br /><br>- HADS (Hospitality Anxiety and Depression Scale, Zigmond & Snaith, 1983)<br /><br>- FEEL-E (Emotional Adjustment Questionnaire for Adults, Grob & Horowitz, 2014)<br /><br>- BDI (Becks Depression Inventory, Beck, Steer, & Brown, 1996)<br /><br><br /><br>Biological markers for stress:<br /><br>- heart rate<br /><br>- skin conductance</p><br>