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Clinical Trials/NCT07138768
NCT07138768RecruitingNot Applicable

The Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time (TAT) in Emergency Settings

Tanta University1 site in 1 country136 target enrollmentStarted: August 23, 2025Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
136
Locations
1
Primary Endpoint
Sensitivity of magnetic resonance imaging for acute stroke

Study Overview

Brief Summary

This study aims to evaluate the role of stroke protocol in the early diagnosis and management of acute stroke and its effect on turnaround time (TAT) in emergency settings.

Detailed Description

Acute stroke is a common and often devastating disorder; however, acute treatments that reduce long-term disability are available if patients present within the time window for treatment.

Computed tomography (CT) or magnetic resonance imaging (MRI) has been used in comprehensive stroke centers, although the role of advanced imaging in the improvement of stroke outcome remains controversial.

MRI offers advantages for the assessment of acute stroke. Changes of acute ischaemic injury are detectable sooner with MRI than with CT, especially with diffusion-weighted imaging, and ischaemic stroke diagnosis with MRI has greater interobserver and intraobserver reliability than CT, even in readers with little experience.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Age ≥18 years.
  • •Both sexes.
  • •Patients with acute stroke who are admitted to the emergency department.

Exclusion Criteria

  • •Contraindications to magnetic resonance imaging (MRI) or computed tomography (CT).
  • •Symptoms strongly suggestive of subarachnoid hemorrhage.
  • •Initiation of antithrombotic or thrombolytic treatment before the completion of both scans.
  • •Inability to complete both scans in time to allow thrombolytic treatment within three h of the onset of symptoms.
  • •Uncontrollable hypertension.
  • •Pregnant or lactating women.

Outcomes

Primary Outcomes

Sensitivity of magnetic resonance imaging for acute stroke

Time Frame: Immediately post-procedure (Up to 1 hour)

Sensitivity of magnetic resonance imaging for acute stroke will be recorded.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Hend Mohammed Mansour

Lecturer of Emergency Medicine and Trauma, Faculty of Medicine, Tanta University, Tanta, Egypt.

Tanta University

Study Sites (1)

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