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Clinical Trials/ISRCTN86284615
ISRCTN86284615
Completed
Not Applicable

Heart failure revascularisatio

Medical Research Council (MRC) (UK)0 sites800 target enrollmentOctober 18, 2000
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ConditionsHeart failure with left ventricular systolic dysfunctionCirculatory System

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart failure with left ventricular systolic dysfunction
Sponsor
Medical Research Council (MRC) (UK)
Enrollment
800
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
October 18, 2000
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional

Investigators

Sponsor
Medical Research Council (MRC) (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Heart failure (in the investigators' opinion) with left ventricular systolic dysfunction (ejection fraction less than 35%) requiring chronic diuretic therapy
  • •2\. Coronary disease as the cause of heart failure as evidenced by a history of previous myocardial infarction, previous revascularisation or previous angiography
  • •3\. Stress\-induced myocardial ischaemia or evidence of myocardial hibernation/stunning affecting five or more left ventricular segments in a 16\-segment model. The core laboratories will make the decision about whether the test identifies a sufficient volume of affected myocardium

Exclusion Criteria

  • •1\. Patients who are not candidates for Coronary Artery Bypass Graft (CABG) because of frailty or serious co\-morbidity (eg:\- severe lung disease, metastatic carcinoma)
  • •2\. Unstable angina, myocardial infarction or stroke within the preceding two months
  • •3\. Inability to give written informed consent
  • •4\. Unwilling to consent to being contacted directly by staff at the data centre or unwilling to allow their hospital notes to be copied and sent to the data centre
  • •5\. Patients being considered for revascularisation for the relief of chest pain (angina) or valve surgery
  • •6\. Patients involved in another randomised controlled trial

Outcomes

Primary Outcomes

Not specified

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