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临床试验/NL-OMON55621
NL-OMON55621已完成不适用

Vascular reactivity in patients with heart failure, ex- and in vivo vasoresponsiveness - VASOR

eids Universitair Medisch Centrum0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • - Diagnosed with heart failure in line with the European Society of Cardiology
  • guidelines;
  • - Left ventricular ejection fraction <=<35%;
  • - Undergoing cardiac surgery on CPB., Group 2:
  • - Not diagnosed with heart failure;
  • - Left ventricular ejection fraction >50%;
  • - Undergoing cardiac surgery on CPB.

排除标准

  • A potential subject who meets any of the following criteria will be excluded
  • from participation in the phase 1 of this study:
  • - Age <18 years;
  • - Incapacitated adults;
  • - Emergency operation;
  • - Patients in need of moderate of high dosages of intravenous inotropic support
  • (>4 gamma dobutamine or dopamine), vasopression and/or mechanical support;
  • - Patients with aortic valve insufficiency > grade 1;
  • - Patients using a daily dosage of nitroglycerine or isosorbide dinitrate;
  • - Patients using alpha blockers.
  • For phase 2, patients that meet any of the following criteria will be excluded
  • from the study:
  • - Age <18 years;
  • - Incapacitated adults;
  • - Emergency operation;
  • - Patients in need of moderate or high dosages of intravenous inotropic support
  • (>4 gamma dobutamine or dopamine) and/or vasopression;
  • - Patients using a daily dosage of nitroglycerine or isosorbide dinitrate;
  • - Patients using alpha blockers.

研究者

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