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Clinical Trials/NL-OMON55621
NL-OMON55621
Completed
N/A

Vascular reactivity in patients with heart failure, ex- and in vivo vasoresponsiveness - VASOR

eids Universitair Medisch Centrum0 sites60 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Heart failure
Sponsor
eids Universitair Medisch Centrum
Enrollment
60
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • \- Diagnosed with heart failure in line with the European Society of Cardiology
  • guidelines;
  • \- Left ventricular ejection fraction \<\=\<35%;
  • \- Undergoing cardiac surgery on CPB., Group 2:
  • \- Not diagnosed with heart failure;
  • \- Left ventricular ejection fraction \>50%;
  • \- Undergoing cardiac surgery on CPB.

Exclusion Criteria

  • A potential subject who meets any of the following criteria will be excluded
  • from participation in the phase 1 of this study:
  • \- Age \<18 years;
  • \- Incapacitated adults;
  • \- Emergency operation;
  • \- Patients in need of moderate of high dosages of intravenous inotropic support
  • (\>4 gamma dobutamine or dopamine), vasopression and/or mechanical support;
  • \- Patients with aortic valve insufficiency \> grade 1;
  • \- Patients using a daily dosage of nitroglycerine or isosorbide dinitrate;
  • \- Patients using alpha blockers.

Outcomes

Primary Outcomes

Not specified

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