General Practitioner's Place in the Treatment of Fracture Osteoporosis in the Elderly

Completed

• Conditions: Osteoporosis

• Registration Number: NCT03402958
• Lead Sponsor: Rennes University Hospital

Brief Summary

Osteoporosis is a major public health problem. Its screening and its treatment remain largely insufficient while therapies have demonstrated their effectiveness. In the event of a severe fracture, the update of the 2016/2017 recommendations, prepared by the Research and Information Group on Osteoporosis and the French Rheumatology Society, concerning osteoporosis recommends a specific treatment with bisphosphonates as first-line treatment, without bone densitometry, regardless of age. The frequency of prescribing anti-osteoporotic treatment as an outpatient after a fracture of the upper extremity of the femur is very low (2% to 21% according to the studies). The main factors associated with non-prescription found are co-morbidities (charlson score\> 6), dementia, obesity (BMI\> 30), chronic alcoholism, male sex, polypharmacy\> 4, age. Conversely, the factors associated with prescribing are recurrent falls (\> 2 / year), a history of osteoporotic fracture, an Iso Resource Group\> 3, female sex, and corticosteroid therapy.

Detailed Description

1. / The collection of patients' characteristics upon admission will be based on the computerized patient file and the paper file: socio-demographic data, co-morbidities, functional status, entry / exit treatments, place of residence, source, balance sheet hospital.

2. / Determination with the treating doctor or the pharmacist of the prescriptions of the anti-osteoporotic treatments at 6 months of the hospital care.

3. / Research factors associated with the prescription (or non-prescription) of anti-osteoporotic treatments.

Study Timeline

• Study First Submitted: 2018-01-10
• Study First Submitted QC: 2018-01-17
• Study First Posted: 2018-01-18
• Study Start: 2018-03-28
• Primary Completion: 2018-03-28
• Study Completion: 2018-03-28
• Status Verified: 2018-09
• Last Update Submitted: 2018-09-20
• Last Update Posted: 2018-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Subjects aged 75 or over (hospitalization criteria in the pathway), admitted to the ortho-geriatric ward of the Saint Malo Hospital Center, treated for a fracture of the upper extremity of the femur.

Exclusion Criteria

• High-energy fracture, pathological fractures (infection, tumor), persons of legal age subject to legal protection (safeguard of justice, guardianship, guardianship), persons deprived of their liberty.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of prescription of anti-osteoporosis treatments.	6 months after surgical management for fracture of the upper end of the femur

Secondary Outcome Measures

Name	Time	Method
Factors associated with the sub-prescription.	Through study completion, an average of 4 months	The main factors associated with non-prescription found are co-morbidities (charlson score\> 6), dementia, obesity (BMI\> 30), chronic alcoholism, male sex, polypharmacy\> 4, age. Conversely, the factors associated with prescribing are recurrent falls (\> 2 / year), a history of osteoporotic fracture, an Iso Resource Group\> 3, female sex, and corticosteroid therapy.

Trial Locations

Locations (1)

Hospital Center of Saint-Malo; 🇫🇷 Saint-Malo, Britain, France