Six Month Morbidity and Mortality among Intensive Care Unit Patients on life sustaining therapy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Assessment of survival and functional outcomes in critically ill patients requiring life-sustaining treatment.
研究概览
简要总结
Patients who survive critical illnesses requiring life-sustaining therapy in intensive care unit (ICU) experience immense difficulties in physical, psychological and cognitive functions. Majority research focuses on immediate outcomes with limited evidence on long-term outcomes of such patients.
Objective is to study the six-month mortality and morbidity among critically ill patients requiring life sustaining therapy.
It is a prospective, single centre, cohort study medical or surgical ICU patients admitted to ICU for a minimum of 3 consecutive days and required life sustaining therapy in terms of mechanical ventilation for 48 hours or vasopressor infusion for 24 hours or both. Cognitive and physical function outcomes at baseline (1-month before the admission) and at six months were noted. Six-month mortality rate and return to normal baseline function were assessed.
240 patients enrolled. All survivors had returned to their place of residence. Implementing cognitive and physical rehabilitation in such patients is essential to achieve optimal outcomes after discharge from ICU.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Adults who were admitted to either medical or surgical ICU patients for a minimum of 3 consecutive days and required life-sustaining therapy.
排除标准
- •Patients below the age of 18 years.
- •Patients whose long-term follow-up was not possible.
- •Incarcerated patients, enrolment in the study for previous ICU admission, neurosurgical and trauma patients that needed ICU admission were excluded.
- •Patients who were unfit for consenting and no legally acceptable relatives were available for consenting.
结局指标
主要结局
Assessment of survival and functional outcomes in critically ill patients requiring life-sustaining treatment.
时间窗: At discharge and 6 months after the discharge
次要结局
- Validation of Charlson comorbidity index and APACHE II score(At the time of admission and 48 hours after the ICU admission)
研究者
Hemal Navin Shah
Mahatma Gandhi Medical College and Hospital