A clinical trial to study the decrease of hypotension associated with the induction dose of propofol
Phase 1
- Conditions
- Health Condition 1: I00-I99- Diseases of the circulatory system
- Registration Number
- CTRI/2020/04/024832
- Lead Sponsor
- Department Of Anesthesiology and Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients undergoing elective surgery under general anaesthesia.
2.Patients aged 18-60 years.
3.Patients of either sex.
4.Patients coming under American Society of Anesthesiologists physical status I,II(Annexure I).
Exclusion Criteria
1.Patients who are unwilling to participate in the study
2.Patients who are allergic to any of the study drugs
3.Patients scheduled for emergency surgery
4.Patients with history of uncontrolled hypertension and diabetes mellitus
5.Peripheral vascular disease
6.Ischemic heart disease
7.Cardiac arrhythmias
8.Morbid obesity (BMI >35 kg/m2)
9.Pregnant and lactating women
10.Patients with psychiatric abnormalities
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart rate , systolic blood pressure , diastolic <br/ ><br>blood pressure and mean arterial pressure will be recorded.Timepoint: Heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure are <br/ ><br>Measured at first, second, third, fourth and fifth minute immediately after induction with propofol <br/ ><br>
- Secondary Outcome Measures
Name Time Method umber of episodes of hypertension, <br/ ><br>hypotension, bradycardia and tachycardiaTimepoint: during study period.