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Clinical Trials/NCT03516019
NCT03516019
Completed
N/A

Messaging Intervention Trial in the Electronic Framingham Heart Study (eFHS)

Boston University1 site in 1 country650 target enrollmentMay 19, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cardiovascular Diseases
Sponsor
Boston University
Enrollment
650
Locations
1
Primary Endpoint
Adherence at 3 months to the weekly BP recording
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

In this research the investigators will develop and test an innovative scalable mobile health and digital cardiovascular monitoring system within a longitudinal deeply characterized cohort with three components: 1) smartphone application (app) designed to promote adherence, integrate digital and mHealth information, and facilitate communication with participants and researchers; 2) smartwatch activity monitoring using the Apple iWatch; and 3) home blood pressure (BP) monitoring using the Withings blood pressure device.

The objective of the messaging trial is to test the effect of messaging strategies on improving participants' long-term use of and engagement with our selected mobile health technologies and on increasing response rate of survey data collection.

Detailed Description

The research design includes a cohort eFHS Study and an embedded randomized factorial trial on a subset of the cohort. For the primary e-cohort, the investigators will build a custom mobile app for use within the Framingham Heart Study (FHS) to digitally collect data, compare it against research clinic-collected data, quantify risk factor burden, and perform CVD risk prediction. The app development will focus on 1) CVD risk factor data that would benefit from more frequent ascertainment than the every four to eight year FHS examination cycles; 2) circumstances where in vivo assessment may be superior to clinic-based assessment; 3) key endpoints of the FHS that are considered FHS landmarks. In addition to the eFHS App, participants will be offered wireless devices (Withings BP) to measure blood pressure and an Apple Watch to measure heart rate and steps per day. For the messaging trial, the investigators will conduct a randomized factorial trial phase to test the effect of messaging strategies. Participants will be sent a weekly notification through the eFHS app. Participants will be randomly allocated to one of 8 groups defined according to the following: using personalized reminder messaging vs. standard neutral messaging; notification sent on a weekday vs. weekend; notification sent in the morning vs. the evening. The three main comparisons will be simultaneously evaluated according to a 2x2x2 factorial design.

Registry
clinicaltrials.gov
Start Date
May 19, 2018
End Date
March 23, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Participants who do not meet the inclusion criteria

Outcomes

Primary Outcomes

Adherence at 3 months to the weekly BP recording

Time Frame: 3 months

proportion of participants who submit their weekly blood pressure measurement at 3 months

Adherence at 3 months to the weekly HR recording

Time Frame: 3 months

proportion of participants who submit their weekly heart rate measurement at 3 months

Secondary Outcomes

  • Adherence at one month to the weekly BP recording(1 month)
  • Adherence at one month to the weekly HR recording(1 month)

Study Sites (1)

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