Evaluation of Oxygen Consumption and Energy Expenditure During Spontaneous Breathing Trial - A Randomized Crossover Controled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Measurement of oxygen consumption through indirect calorimetry.
研究概览
简要总结
The purpose of this study is to compare the oxygen consumption and energy expenditure during the spontaneous breathing trial.
详细描述
Patients is going to submit to the 2 spontaneous breathing trial ( Automatic tube compensation plus continuous positive airway pressure and continuous positive airway pressure without automatic tube compensation. The oxygen consumption and energy expenditure is going to measure during the spontaneous breathing trial by indirect calorimetry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •IMPROVEMENT OR RESOLUTION OF THE UNDERLYING CAUSE OF DISEASE
- •INTUBATED PATIENTS>24h
- •PaO2 GREATER THAN 60 mmHg WITH FiO2 LESS THAN 40%
- •PEEP=5 cmH2O
排除标准
- •CARDIOVASCULAR INSTABILITY
- •FEBRILE OR HYPOTHERMIA
- •CHEST DRAINAGE
- •RESPIRATORY RATE/TIDAL VOLUME RATIO GREATER THAN 105
- •PREGNANCY
- •FAIL IN THE SPONTANEOUS BREATHING TRIAL
- •LEAKS IN THE CIRCUIT
- •AGITATION
- •NOT ACCEPT PARTICIPATE IN THE STUDY
结局指标
主要结局
Measurement of oxygen consumption through indirect calorimetry.
时间窗: The measurement is during the spontaneous breathing trial, 30 minutes.
Measurements using indirect calorimetry for determination of oxygen consumption
次要结局
- Measurement of energy expenditure through indirect calorimetry(The measurement is during the spontaneous breathing trial, 30 minutes.)
研究者
Alessandra Fabiane Lago
ALESSANDRA FABIANE LAGO
University of Sao Paulo