Evaluation of Oxygen Consumption and Energy Expenditure During Spontaneous Breathing Trial - A Randomized Crossover Controled Trial.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiratory Failure
- Sponsor
- University of Sao Paulo
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Measurement of oxygen consumption through indirect calorimetry.
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The purpose of this study is to compare the oxygen consumption and energy expenditure during the spontaneous breathing trial.
Detailed Description
Patients is going to submit to the 2 spontaneous breathing trial ( Automatic tube compensation plus continuous positive airway pressure and continuous positive airway pressure without automatic tube compensation. The oxygen consumption and energy expenditure is going to measure during the spontaneous breathing trial by indirect calorimetry.
Investigators
Alessandra Fabiane Lago
ALESSANDRA FABIANE LAGO
University of Sao Paulo
Eligibility Criteria
Inclusion Criteria
- •IMPROVEMENT OR RESOLUTION OF THE UNDERLYING CAUSE OF DISEASE
- •INTUBATED PATIENTS\>24h
- •PaO2 GREATER THAN 60 mmHg WITH FiO2 LESS THAN 40%
- •PEEP=5 cmH2O
Exclusion Criteria
- •CARDIOVASCULAR INSTABILITY
- •FEBRILE OR HYPOTHERMIA
- •CHEST DRAINAGE
- •RESPIRATORY RATE/TIDAL VOLUME RATIO GREATER THAN 105
- •PREGNANCY
- •FAIL IN THE SPONTANEOUS BREATHING TRIAL
- •LEAKS IN THE CIRCUIT
- •AGITATION
- •NOT ACCEPT PARTICIPATE IN THE STUDY
Outcomes
Primary Outcomes
Measurement of oxygen consumption through indirect calorimetry.
Time Frame: The measurement is during the spontaneous breathing trial, 30 minutes.
Measurements using indirect calorimetry for determination of oxygen consumption
Secondary Outcomes
- Measurement of energy expenditure through indirect calorimetry(The measurement is during the spontaneous breathing trial, 30 minutes.)