Comparison of three intravenous fluids used in the treatment of children admitted to the paediatric intensive care unit

Phase 1

Completed

• Conditions: Critically ill children; Emergency medicine - Resuscitation; Emergency medicine - Other emergency care

• Registration Number: ACTRN12619001244190
• Lead Sponsor: niversity of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-09
• Study Completion: 2021-07-15
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 524

Inclusion Criteria

1. All patients – birth to an age of less than 16 years - admitted to the Paediatric Intensive Care Unit (and)
2. Attending clinician decides that intravenous fluid therapy is required
3. Admission Na >130mmol/L
4. New admissions to ICU within the last 24 hours

Exclusion Criteria

1. Age greater than or equal to 16 years.
2. Patients admitted with a cardiac condition.
3. Received intravenous fluid therapy for >4 hours in PICU.
4. Patients admitted to the ICU with disease-specific protocols that necessitate specific fluid requirements such as: the treatment of burns; following liver transplantation surgery; post renal transplant surgery; diabetic ketoacidosis.
6. Patients with traumatic brain injury or those considered at risk of developing cerebral edema
7. Patients with pre-existing kidney disease (chronic kidney disease as defined by KDIGO criteria or under the ongoing care of a nephrologist)
8. Oncology patients who need hyperhydration.

Study & Design

• Study Type: Interventional
• Study Design: Not specified