Fluid replacement in patients undergoing neurosurgery
Not Applicable
Recruiting
- Conditions
- Patients with intracranial tumor or aneurysmE04.525.190C10.228.140.300.510.600
- Registration Number
- RBR-2592hd
- Lead Sponsor
- Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, UNESP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Patients undergoing neurosurgery, tumor resection, or aneurysm clamping and who are 18 years of age and older and classified as physical status ASA I, II, and III, according to the American Society of Anesthesiologists classification.
Exclusion Criteria
Patients or legal representative who do not accept to participate in the study, with refusal to sign the consent form; patients under 18 years old; any other neurosurgical procedure other than tumor resection or aneurysm clipping (head trauma, ventriculo-peritoneal shunt, etc.), patients with chronic kidney injury, pre-existing abnormality of acid-base and electrolyte disorder, pregnant women and patients in use of previous diuretics.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To verify the alteration of the acid-base and hydroelectrolytic balance by means of arterial blood gas measurement (PaO2, PaCO2, BE, HCO3), plasma electrolytes (Na +, K +, calcium, mg ++) and plasma lactate
- Secondary Outcome Measures
Name Time Method Hemodynamic stability verified by measuring blood pressure, heart rate, oxygen saturation and expired CO2 pressure<br>Presence of acute kidney injury assessed by diuresis and plasma creatinine<br>Surgical condition assessment performed by the surgeon<br>Presence of postoperative complications (extubation time (min)<br>ICU stay (days)<br>Length of hospital stay (days)<br>Mortality at 24 hours, seven, 30 and 90 days