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COMPARISON OF TWO DIFFERNT TYPE OF FLUID THERAPIES FOR INTRAOPERATIVE BRAIN CONDITION, IN PATIENTS UNDERGOING BRAIN TUMORS SURGERY

Not Applicable
Completed
Conditions
Health Condition 1: null- ASA I AND II PATIENTS UNDERGOING SURGERY FOR SUPRATENTORIAL BRAIN TUMORSHealth Condition 2: C712- Malignant neoplasm of temporal lobe
Registration Number
CTRI/2016/09/007274
Lead Sponsor
PGIMER CHANDIGARH
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
110
Inclusion Criteria

(1)Patients scheduled to undergo craniotomy for supratentorial tumors

(2)ASA-I and II patients.

(3)18 â?? 65 yrs of age

Exclusion Criteria

(1)Pre-operative hypernatremia or hyponatremia (serum Na <130 or >150mEq/L).

(2)History of congestive heart failure, kidney disease, chronic obstructive airway disease.

(3)History of ventriculoperitoneal (VP) shunt.

(4)Initial serum osmolarity >320mosm/kg.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Effect of 0.9% saline versus Plasma-Lyte A on intraoperative degree of brain relaxation in patients undergoing surgery for supratentorial tumors.Timepoint: AT THE TIME OF BONE FLAP ELAVATION , DURING CRANIOTOMY FOR TUMOR RESECTIO
Secondary Outcome Measures
NameTimeMethod
<br/ ><br>Effect of 0.9% saline versus Plasma-Lyte A on <br/ ><br>Hemodynamics variable, Electrolyte changes, Serum osmolarity, Jugular venous oximetry and metabolism variabl,Post op complication, Duration of Hospital stay, MRSA at discharge <br/ ><br> <br/ ><br>Timepoint: till patient discharge or death
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