Balanced fluid therapy and early kidney function in patients undergoing renal transplantatio

Phase 4

Completed

• Conditions: Renal failure; Renal transplantation; Renal and Urogenital - Kidney disease; Anaesthesiology - Anaesthetics; Surgery - Other surgery

• Registration Number: ACTRN12612000023853
• Lead Sponsor: Austin Hospital, Department of Anaeasthesia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Adult patients (age > 18years)
2. Deceased donor renal transplantation (heart-beating or non heart-beating)

Exclusion Criteria

1. Preoperative hyperkalaemia (serum potassium > 6.0 mmol/L
2. Pregnancy
3. Chronic liver disease (liver function tests > 1.5 X normal value)
4. Known allergic reaction to study solutions
5. Combined liver-kidney transplantation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Standard base deficit as measured by a automated blood gas analyser[Mesaured immediately post surgery in the Post Anaesthesia Care Unit and at 24 hours & 48 hrs postoperatively];Serum potassium[Measured immediately post surgery in the Post Anaesthesia Care Unit and at 24 hours & 48 hrs postoperatively];Serum creatinine[Measured immediately post surgery in the Post Anaesthesia Care Unit and at 24 hours & 48 hrs postoperatively and then prior to hospsital discharge]