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临床试验/NCT00951821
NCT00951821已完成不适用

Concurrent Treatment for Parents and Adolescents Who Attempt Suicide

Brown University1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2009年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
Beck Depression Inventory - Adolescent Report, Change in Symptom Level

研究概览

简要总结

This study will develop an integrated treatment for adolescents who are depressed and suicidal and their parents who are depressed and have a history of suicidality.

详细描述

Depression, like many psychiatric disorders, has a genetic component that makes it more likely that members of the same family will have the disorder. Depression in parents, particularly mothers, may put the children at greater risk for depression. When an adolescent whose parent is depressed develops depression himself or herself, treating both the parent and the adolescent may be more effective than treating only the adolescent. This study will test a depression treatment that targets depressed suicidal adolescents with a parent or primary caretaker who is also depressed and has a history of suicidality.

Participation in this study will last 6 months. Participants will be randomly assigned to receive either concurrent parent and adolescent treatment or adolescent only treatment. For those assigned to concurrent treatment, both the adolescent participants and one of their parents will receive individual cognitive behavioral therapy (CBT) counseling sessions and joint family counseling sessions. In the adolescent only treatment condition, adolescent participants will receive individual CBT sessions, but parents will not, and both will receive joint family sessions. Counseling sessions will last 1 hour and occur weekly for 3 months, and then every other week for 3 months. CBT identifies and attempts to change problematic thought patterns. All participants will receive medication consultation if necessary.

Participants will complete assessments at baseline, post-treatment, and 6 months after completing treatment. These assessments will include questionnaires and interviews about depression, suicidal thoughts, mood regulation, behavioral problems, and family. At post-treatment and the 6-month follow-up, participants will also be asked to give feedback about the counseling, medication consultation, and their satisfaction.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
12 Years 至 17 Years(Child)
性别
All
接受健康志愿者
否

入选标准

  • •for Adolescents:
  • •Lives at home with at least one parent or guardian
  • •Speaks English
  • •Must have made a suicide attempt and be diagnosed with major depressive disorder (MDD)
  • •Inclusion Criteria for Primary Caretakers:
  • •Speaks English
  • •Current diagnosis of MDD and a history of suicidality

排除标准

  • •for Adolescents:
  • •Judged to have developmental or cognitive delays or psychotic disorders on the basis of a standard psychiatric exam
  • •Diagnosis of bipolar disorder or a substance dependence (people with a diagnosis of substance abuse are eligible)
  • •Only one adolescent per family is eligible
  • •Exclusion Criteria for Primary Caretakers:
  • •Diagnosis of bipolar disorder or substance dependence
  • •If taking antidepressants, not on a stable dose for 3 months

研究组 & 干预措施

Concurrent treatment

Experimental

Concurrent treatment - experimental condition: Adolescent participants and their parents will receive concurrent cognitive behavioral therapy.

干预措施: Concurrent treatment (Behavioral)

Adolescent treatment only

Active Comparator

Adolescent treatment only - Active Comparator: Only adolescent participants will receive cognitive behavioral therapy.

干预措施: Adolescent treatment only (Behavioral)

结局指标

主要结局

Beck Depression Inventory - Adolescent Report, Change in Symptom Level

时间窗: 12 months

self-report measure of depressed mood - range of scores 0 to 60; higher scores indicate worse depression. The data in this outcome refer to change from baseline to 12 month follow-up, per the adolescent self-report.

次要结局

  • Beck Suicide Scale - Adolescent Response(Measured at 12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Anthony Spirito

Professor

Brown University

研究点 (1)

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