Adenovirus Keratoconjunctivitis and Ophtalmology

• Conditions: Adenoviral Keratoconjunctivitis

• Registration Number: NCT04417244
• Lead Sponsor: University Hospital, Clermont-Ferrand

Brief Summary

Adenovirus conjunctivitis is an epidemic disease registered as a common occupational disease for ophthalmologists and orthoptists. It can leave corneal sequelae even several years after infection.

The primary aim of the study is to investigate the prevalence of these sequelae in the at-risk population of ophthalmologists and orthoptist.

Secondary aim are to describe administrative procedures (occupational disease declaration and sick leave),infections characteristics; and risk factors.

Detailed Description

Adenovirus conjunctivitis is an epidemic disease registered as a common occupational disease for ophthalmologists and orthoptists. It can leave corneal sequelae even several years after infection.

The investigation tream create a nationwide anonymous retrospective questionnaire using the secure internet application REDCap® to build and manage the questionnaire addressed to ophtalmologists (interns, graduates and retirees) and orthoptists.

Investigator collect several characteristics such as general characteristics (sex, age range, profession), administrative procedure declaration (occupational disease declaration, sick leave, cessation of surgery); infection characteristics (bilaterality, season, anteriority, sequels, current therapy, professional discomfort), risk factor (refractive surgery history, wearing of eyeglasses or contact lenses, smoking, or corticosteroid therapy).

The primary aim of the study is to investigate the prevalence of these sequelae in the at-risk population of ophthalmologists and orthoptist. Secondary aim are to describe administrative procedures (occupational disease declaration and sick leave), infections characteristics; and risk factors such as a refractive surgery history, the wearing of eyeglasses or contact lenses, smoking, or corticosteroid therapy.

Study Timeline

• Study Start: 2019-10-21
• Status Verified: 2020-05
• Study First Submitted: 2020-06-02
• Study First Submitted QC: 2020-06-03
• Last Update Submitted: 2020-06-03
• Study First Posted: 2020-06-04
• Last Update Posted: 2020-06-04
• Primary Completion: 2022-10
• Study Completion: 2022-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Ophtalmologist or orthoptist (interns, graduates and retirees)
• French

Exclusion Criteria

• Foreign practitionner

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
general characteristics - Sex	Day 1	general characteristics - Sex
epidemiology characteristics	Day 1	history of adenovirus keratoconjunctivitis; history of sequels
general characteristics - Age range	Day 1	general characteristics - Age range
general characteristics - Profession	Day 1	general characteristics - Profession

Secondary Outcome Measures

Name	Time	Method
administrative procedure declaration	Day 1	occupational disease declaration, sick leave, cessation of surgery and duration
risk factor	Day 1	refractive surgery history, wearing of eyeglasses or contact lenses, smoking, corticosteroid therapy
infection characteristics	Day 1	bilaterality, season, anteriority, sequels, current therapy, professional discomfort

Trial Locations

Locations (1)

University hospital, Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France