Assessment of tissue perfusion of pancreatic cancer by means of Intravoxel incoherent motion MRI and CT perfusion: Correlation with histological microvessel density as ground truth.

• Conditions: C25; Malignant neoplasm of pancreas

• Registration Number: DRKS00022227
• Lead Sponsor: Diagnostische und Interventionelle Radiologie Universitätsklinikum Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-07-21
• Study Start: 2020-06-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

1) Presence of a mass suspicious of pancreatic cancer in a previous CT and/or MRI. 2) Scheduled surgery with planned resection of the mass.

Exclusion Criteria

1) General contraindications for the application of iodinated contrast agents. 2) MR-unsafe foreign bodies. 3) Previous treatment for pancreatic carcinoma. 4) inability to reproduce the breathing technique.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of perfusion measurements by a) IVIM DW MRI and b) CT-perfusion.

Secondary Outcome Measures

Name	Time	Method
Correlation of a) perfusion measurements by imaging (IVIM DW MRI and CT perfusion) and b) histopathological microvessel density.