Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning
- Registration Number
- NCT01201954
- Lead Sponsor
- Universidade Federal de Pernambuco
- Brief Summary
Evaluate the effectiveness of the use of a 24% sucrose solution for pain management of preterm infants during endotracheal suctioning.
- Detailed Description
Many infants admitted to neonatal intensive care unit (NICU) undergo repeated invasive procedures. Recent studies have shown that the oral sucrose administration to neonates is safe and effective for pain relief during heel stick and venipuncture.Most data suggest the investigation of the effect of sucrose in other painful procedures such as in ventilated newborns.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 43
- preterm infants
- over 12 hours of life
- intubated
- clinically stable
- without use of analgesics or sedatives
- preterms with congenital malformations
- preterms with genetic syndromes
- preterms with Apgar score at 5´<7
- preterms with meningitis
- preterms with diagnosed of necrotizing enterocolitis Ouvir Ler foneticamente
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description sucrose sucrose 0,5 ml/kg of sucrose administered 2 minutes prior the procedure sterile water sucrose 0,5 ml/kg of sterile water administered 2 minutes prior the procedure
- Primary Outcome Measures
Name Time Method clinical pain score within the first twelve hours after clinical stabilization, the PIPP will be done. The tool that will be used is PIPP = Premature Infant Pain Profile. This avaliation begins prior to suctioning until 30 seconds after suctioning. Each infant will be avaliated 2 times (with sucrose and with placebo). The 2 avaliations in the same day.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hospital Agamenon Magalhães, Hospital Barão de Lucena
🇧🇷Recife, Pernambuco, Brazil