Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning: a Randomized Clinical Trial
Overview
- Phase
- Phase 2
- Intervention
- sucrose
- Conditions
- Pain
- Sponsor
- Universidade Federal de Pernambuco
- Enrollment
- 43
- Locations
- 1
- Primary Endpoint
- clinical pain score
- Status
- Completed
- Last Updated
- 15 years ago
Overview
Brief Summary
Evaluate the effectiveness of the use of a 24% sucrose solution for pain management of preterm infants during endotracheal suctioning.
Detailed Description
Many infants admitted to neonatal intensive care unit (NICU) undergo repeated invasive procedures. Recent studies have shown that the oral sucrose administration to neonates is safe and effective for pain relief during heel stick and venipuncture.Most data suggest the investigation of the effect of sucrose in other painful procedures such as in ventilated newborns.
Investigators
Eligibility Criteria
Inclusion Criteria
- •preterm infants
- •over 12 hours of life
- •intubated
- •clinically stable
- •without use of analgesics or sedatives
Exclusion Criteria
- •preterms with congenital malformations
- •preterms with genetic syndromes
- •preterms with Apgar score at 5´\<7
- •preterms with meningitis
- •preterms with diagnosed of necrotizing enterocolitis Ouvir Ler foneticamente
Arms & Interventions
sucrose
0,5 ml/kg of sucrose administered 2 minutes prior the procedure
Intervention: sucrose
sterile water
0,5 ml/kg of sterile water administered 2 minutes prior the procedure
Intervention: sucrose
Outcomes
Primary Outcomes
clinical pain score
Time Frame: within the first twelve hours after clinical stabilization, the PIPP will be done.
The tool that will be used is PIPP = Premature Infant Pain Profile. This avaliation begins prior to suctioning until 30 seconds after suctioning. Each infant will be avaliated 2 times (with sucrose and with placebo). The 2 avaliations in the same day.