The effect of probiotics on infectious disease and DNA damage in lymphocytes of dialysis patients
Phase 3
- Conditions
- Chronic kidney disease.Chronic kidney disease
- Registration Number
- IRCT2016103130603N1
- Lead Sponsor
- Shahroud University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
over 18 years of age, glomerular filtration rate less than 15 ml/min, having routine diets
Exclusion Criteria
infectious diseases, pregnancy (for female participants), autoimmune or immunosuppressive diseases, taking immunosuppressive drugs or antibiotics, lactose intolerance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of endotoxin. Timepoint: Before and after the intervention (6 months). Method of measurement: Limulus Amebocyte Lysate (LAL) kit.;DNA Damage of peripheral blood mononuclear lymphocytes. Timepoint: Before and after the intervention (6 months). Method of measurement: Comet Assay.;Faecel level of endotoixn. Timepoint: Before and after the intervention (6 months). Method of measurement: Limulus Amebocyte Lysate (LAL) kit.
- Secondary Outcome Measures
Name Time Method