Comparison in frequency of hypotension during sedation of propofol and remimazolam in spinal anesthesia in hip surgery patients: a randomized controlled clinical trial
Not Applicable
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0006873
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 78
Inclusion Criteria
* ASA physical status 1-3
* Age: Adults from 20 to 64 years of age
* Patients scheduled for hip surgery under spinal anesthesia and sedation using propofol or remimzolam
Exclusion Criteria
* Denial of consent
* Uncontrolled hypertension, hyperthyroidism, incommunicable dementia, symptomatic coronary artery disease
* Those who are allergic to propofol, fentanyl, or bupivacaine
* Contraindications to spinal anesthesia such as coagulopathy, severe aortic stenosis/mitral stenosis, active infection on lumbar region
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The purpose of this study was to investigate whether there was a difference in the incidence of hypotension during surgery between the two groups. (MBP<65)
- Secondary Outcome Measures
Name Time Method The incidence of intraoperative hypertension (SBP>160) ;Total dose of phenylephrine administered during surgery ;Total amount of fluid infused during surgery ;Number of episodes of hypotension in the PACU( post anesthesia care unit) after surgery (MBP<65) ;postoperative complications ( cardiovascular, neurologica, respiratory, delirium, renal function, postoperative nausea and vomiting, etc) ;Time to recovery after surgery (time until modified observer's alertness/sedation scale (MOAA/S) score of 5 or higher after stopping drug injection)