Comparison of Inflammatory Markers, Magnetic Resonance Spectroscopy Characteristics And Natural History of Liver Cirrhotics with Minimal And Grade 1 Hepatic Encephalopathy - NI

Govind Ballabh Pant Institute of Post Graduate Medical Education and Research, New Delhi0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年11月13日

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•Patients with evidence of cirrhosis on ultrasound, fibroscan or liver histopathology if available

•Contraindications of MR spectroscopy including cardiac pacemaker without MRI compatibility, implanted cardioverter defibrillator, cochlear implant, claustrophobia etc.
•Patients with hepatic encephalopathy of Grade 2 or higher (By West Haven criteria) in the pastHistory of GI bleed in last one-month, spontaneous bacterial peritonitis (SBP) on prophylaxis or hepatorenal syndrome (HRS) and patients of acute on chronic liver failure (ACLF).
•Patients who have received Lactulose, Rifaximin, LOLA, probiotics or anti-inflammatory drugs such as steroids and NSAIDs.
•History of use of psychotropic drugs in last 6 weeks
•Poor vision precluding neuropsychological assessment.
•Patients with known neurological illness
•History of TIPSS or Shunt surgery
•Active ongoing infection
•Hepatocellular carcinoma or severe medical problems such as congestive heart failure, pulmonary disease, or neurological or psychiatric disorder.

发起方

Govind Ballabh Pant Institute of Post Graduate Medical Education and Research, New Delhi