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Low Level Laser Therapy Applied in Orthodontic Tooth Movement

Early Phase 1
Completed
Conditions
Orthodontic Appliance Complication
Interventions
Device: Low Level Laser Therapy
Other: Placebo
Registration Number
NCT05695053
Lead Sponsor
China Medical University Hospital
Brief Summary

Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Patients with good oral hygiene
  • 18 years old
  • Patients who required bilateral canine retraction into the extracted premolar
Exclusion Criteria
  • Serious medical history
  • Poor oral hygiene
  • Previous orthodontic treatment
  • Orthognathic surgery or syndromic patients

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
with LLLTLow Level Laser Therapy-
without LLLTPlacebo-
Primary Outcome Measures
NameTimeMethod
Orthodontic tooth movement1-6month

the distance between canine and premolar

Secondary Outcome Measures
NameTimeMethod
bone density after Orthodontic tooth movement1-6month

bone density change around canine

Trial Locations

Locations (1)

China Medical University Hospital

🇨🇳

Taichung City, Taiwan

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