To study the gender-wise difference in Vit B12 and Vit D deficiency, Gender wise categorization of clinical symptoms and reversal of symptoms with appropriate supplementation with vitamin B12 or vitamin D pills
Not yet recruiting
- Conditions
- Vitamin B12 and Vitamin D Normal and deficient subjects
- Registration Number
- CTRI/2021/06/034312
- Lead Sponsor
- Deenanath Mangeshkar Hospital and Research Center Pune
- Brief Summary
**We have designed a studywith the objective to**
**1. assess association ofsymptoms with different levels of B12 deficiency and also gender wisecategorization of the symptoms**
**2. to see the effect of combinedtreatment of B12 and Vit D on VitaminB12, VitaminD, Holotranscobalamin andhomocysteine in Vitamin B12 deficient subjects.**
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- Normal plasma Vitamin B12 and Vitamin D levels 2.
- Plasma Vitamin B12<250 pg/ml and vitamin D > 30 ng/dL 3.
Exclusion Criteria
- 1.Subjects taking B12 supplementation 2.
- Subjects on medication which interferes with B12 absorption and metabolism (e.g. methorexate, anta cids, metformin) 3.
- Subjects with diabetes, cancer, pregnancy., known chronic systemic diseases.
- Age-below18 years.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gender wise differentiation of clinical symptoms and post supplementation reversal of vitamin B12 and Vitamin D deficiency 6 months
- Secondary Outcome Measures
Name Time Method Improvement of vitamin B12 and D status with supplementation 6 months
Trial Locations
- Locations (1)
Clinical Biochemistry (Pathology) and Orthopaedics Department
🇮🇳Pune, MAHARASHTRA, India
Clinical Biochemistry (Pathology) and Orthopaedics Department🇮🇳Pune, MAHARASHTRA, IndiaDr Namita MahallePrincipal investigator9689935996pnmahalle@gmail.com