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临床试验/NCT01127191
NCT01127191已完成不适用

Effect of Prolonged Military Exercises With High Load Carriage, on Neuromuscular Fatigue and Physiological/Biomechanical Responses

Centre Hospitalier Universitaire de Saint Etienne1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2010年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Peripheral fatigue based on electrically-induced force measurement on the same muscle in relaxed condition.

研究概览

简要总结

Land military missions generally combine prolonged walking/moderate-pace-running and other physical actions such as creeping, jumping, shooting,... which are associated with the direct carrying of high to severe loads of equipment and supplies (20-30 to 50 kg) by soldiers. For an infantry section, "typical" intervention phases last about 20-24 h and combine variable intensity grades. Consequently, military mission characteristics are an interesting investigation field of human fatigue. Previous studies have investigated human neuromuscular alterations after prolonged "normal" locomotion exercises [Millet et al., 2004, 2009], thus the aim of this study is to characterize the neuromuscular determinants of fatigue induced by a 24-h Simulated Military Effort (SME) and a 4-h Military Road March (MM), both performed with high load carriage. Additionally, the consequences of fatigue on physiological and biomechanical parameters of locomotion will be investigated.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
30 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • to be a male
  • to have a VO2max > 45ml/min/kg (mean observed value in military subjects)
  • to be aged from 30 to 45
  • to be recently retreated from National Army
  • to be highly experienced in military efforts
  • to be trained in exercises involving load carrying
  • to benefit from a social security insurance

排除标准

  • All subjects with recent (< 3 month) bone, articular or muscle diseases.
  • All subjects presenting a clinic sign of intolerance to testing procedures, especially subjects with knee, ankle, hip or back diseases.
  • All subjects intolerant to muddy or wooded environment.
  • All subjects presenting a clinic sign of intolerance to exercise, and particularly to running or walking while carrying a load
  • All subjects involved at the same time in another medical research
  • All subjects militarily active
  • All subjects with cardiac or pulmonary identified and known diseases

结局指标

主要结局

Peripheral fatigue based on electrically-induced force measurement on the same muscle in relaxed condition.

时间窗: after a a military exercise of 24 hours

Central fatigue quantification based on voluntary and electrically-induced force measurement on activated muscle.

时间窗: after a a military exercise of 24 hours

次要结局

  • Lactatemia, based on subject's arterialized capillary blood samples analysis(after a a military exercise of 24 hours)
  • Oxygen uptake, carbon-dioxide output, energetic-cost of locomotion and respiratory ratio, based on subject's gas exchanges.(after a a military exercise of 24 hours)
  • Walking and running mechanics, measured by an instrumented treadmill(after a a military exercise of 24 hours)
  • Perceived comfort, measured by a 10 cm visual analogic scale (VAS)(after a a military exercise of 24 hours)
  • Muscular electrical activities, based on subject's surface EMG analysis(after a a military exercise of 24 hours)
  • Rate of perceived exertion, measured by the Borg scale ranging from 6 to 20(after a a military exercise of 24 hours)
  • Heart rate frequence(after a a military exercise of 24 hours)
  • Postural equilibration, measured by a piezo-dynamometric double platform(after a a military exercise of 24 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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