ParKinWalk: Physical Activity and Long Group-walking for Motor Impairment and Quality of Life in Parkinson's Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- Università degli Studi di Brescia
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Supervised gait performance dual task gait
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The study will evaluate the impact of exercise training program followed by long-walking onon supervised and unsupervised gait assessment in Parkinson´s disease and control subjects.
Detailed Description
Background: Several studies suggest an impact of physical exercise on walking parameters in Parkinson´s disease (PD) patients. Objective: the present study will evaluate the impact of three months physical exercise training program followed by a group-long walking on motor impairment in PD. Methods: PD patients will be randomized in two arms: one group will be assessed to a training exercise program of three months followed by long-walking in group under the support of physician/physiotherapist and caregivers. A complete motor, cognitive and general assessment will be performed at baseline. The patients will be evaluated under supervised an unsupervised conditions at baseline, before the long-walking, during the walking and after 2 months after the walk.
Investigators
Andrea Pilotto
Principal Investigator
Università degli Studi di Brescia
Eligibility Criteria
Inclusion Criteria
- •Parkinson´s disease diagnosis
- •stable dopaminergic treatment ( stable dose in the last three months before baseline evaluation)
Exclusion Criteria
- •gait impairment due to other medical conditions
- •impulsive compulsive disorder
- •severe depression
Outcomes
Primary Outcomes
Supervised gait performance dual task gait
Time Frame: Changes between baseline, immediately before the long-walking, during the day 1 and day 5 of walk and two months after walk. In the non-active group- supervised and unsupervised assessment will be evaluated after 6 months of usual care.
Step variability using wearing sensors technology in one-minute supervised dual task walking (Rehagait Hasomed as wearing sensors)
unsupervised gait performance normal gait
Time Frame: Changes between baseline, immediately before the long-walking, during the day 1 and day 5 of walk and two months after walk. In the non-active group- supervised and unsupervised assessment will be evaluated after 6 months of usual care.
Step variability using wearing sensors technology in one-day unsupervised walking (GaitUp Physilog sensors)
Supervised gait performance normal gait
Time Frame: Changes between baseline, immediately before the long-walking, during the day 1 and day 5 of walk and two months after walk In the non-active group- supervised and unsupervised assessment will be evaluated after 6 months of usual care.
Step variability using wearing sensors technology in one-minute supervised walking (rehagait, Hasomed as wearing sensors)
Secondary Outcomes
- Unified parkinson´s disease Rating Scale part 3 (0-132 points) Higher scores mean worse outcomes(Changes between baseline, immediately before the long-walking, during the day 1 and day 5 of walk and two months after walk. In the non-active group- the assessment will be evaluated at baseline and after 6 months of usual care.)
- Parkinson´s disease Quality of life questionnaire (PDQ-39) (0-117 points) Lower scores mean worse outcomes(Changes between baseline, immediately before the long-walking, during the day 1 and day 5 of walk and two months after walk. In the non-active group- the assessment will be evaluated at baseline and after 6 months of usual care.)