Effects of a Multidirectional Walking Program on Physical Function and Quality of Life in Hematopoetic Stem Cell Transplant Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- The Physical Performance Test Battery
研究概览
简要总结
This study will determine if a structured walking intervention will help maintain or improve physical activity levels, physical function and quality of life in hematopoietic stem cell transplant patients.
详细描述
The researchers will quantify the decline in physical function of HSCT patients using valid and reliable tests aimed to mimic activities of daily living, quantify cardiovascular health, and quantify muscle power declines. Also, patients will undergo a walking program during their hospitalization, which is designed to increase physical activity levels and maintain and improve physical function and quality of life. Additionally, using valid and reliable questionnaires, the researchers will gauge perception of exercise, quantify current exercise levels, determine preference of exercise programs and counseling, and measure differences in quality of life before and after HSCT treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Be between 40 and 80 years of age
- •Willing and able to provide written informed consent in English
- •Ability to comprehend the purpose of the study
- •Be scheduled to receive an autologous or allogeneic hematopoietic stem cell transplant at Sylvester Comprehensive Cancer Center
- •Have an expected hospital stay of at least 2 weeks
- •Not currently be participating in an exercise training program
排除标准
- •Dementia, altered mental status, or psychiatric condition
- •Received erythropoiesis-stimulating proteins within 4 weeks prior to enrollment
- •Comorbid conditions that would contraindicate exercise testing
- •Undergoing concurrent non-transplant-related chemotherapy or radiation
研究组 & 干预措施
Walk training and transplant
Multidirectional walk training with activity monitoring after bone marrow transplant
干预措施: Walk Training and Transplant (Other)
Activity Monitoring and transplant
Activity monitoring alone after bone marrow transplant.
干预措施: Activity Monitoring and Transplant (Other)
结局指标
主要结局
The Physical Performance Test Battery
时间窗: 10 minutes
Physical Function
次要结局
- Functional Assessment of Cancer Therapy: Bone Marrow Transplant Questionaire Related Quality of Life(20 minutes)
- Patient Reported Outcome Measurement Information System(20 minutes)
研究者
Joseph Signorile
Professor
University of Miami