Glucose in Dialysis Water in Diabetics With Chronic Renal Failure

Phase 4

Completed

• Conditions: Renal Failure, Chronic; Diabetic Nephropathies

• Registration Number: NCT00438503
• Lead Sponsor: Regional Hospital Holstebro

Brief Summary

The purposes are 1. to measure the effect of dialysis with glucose in dialysis water on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin and body temperature, and 2. to analyse the relationship between the changes in blood pressure and changes in vasoactive hormones

Detailed Description

The relationship between blood pressure during dialysis treatment and vasoactive hormones are studied. This includes measurements of plasma concentration of glucose, plasma concentrations og insulin, glucagon, growth hormone, renin, angiotensin II, endothelin

Study Timeline

• Study Start: 2006-05
• Study First Submitted: 2007-02-20
• Study First Submitted QC: 2007-02-21
• Study First Posted: 2007-02-22
• Study Completion: 2007-05
• Status Verified: 2007-09
• Last Update Submitted: 2015-09-14
• Last Update Posted: 2015-09-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

1. Age > 18 years,
2. Both men and women,
3. Dialysis treatment for at least three month due to diabetic nephropathy

Exclusion Criteria

1. Heart failure,
2. Lung insufficiency,
3. Chronic liver disease,
4. Malignant disease,
5. Nephrotic syndrome,
6. Lack of compliance,
7. Unwillingness to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Effect og glucose in dialysis water on blood pressure, plasma glucose and hormones in plasma

Secondary Outcome Measures

Name	Time	Method
Relationship between changes in blood pressure and and changes in hormones

Trial Locations

Locations (1)

Holstebro Hospital; 🇩🇰 Holstebro, Denmark