Examining Representations of Dementia in Fiction and Clinical Narratives
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Mini-Mental State Examination
研究概览
简要总结
This study aims to compare the natural narrative language of patients with Alzheimer's disease and the fictional depictions of dementia in contemporary novels from both neurological and literary perspectives. It investigates the similarities and differences in the deterioration of semantic and episodic memory. The goal is to develop a cross-disciplinary language observation model that enhances early diagnostic understanding, fosters empathy in caregiving, and strengthens medical humanities education.
详细描述
Background: Dementia is a major neurodegenerative disease of concern in aging societies worldwide, with Alzheimer's disease being the most common form. Early symptoms often involve language impairments and narrative disorganization. While neurology has extensively studied semantic memory and pragmatic dysfunction, systematic analysis of natural language narratives remains limited. Meanwhile, contemporary "neuronovels" depict the linguistic and cognitive decline of characters with dementia in highly realistic and emotionally resonant ways, providing narrative insights that may complement clinical observations. This project uses novels such as The Tunnel by A. B. Yehoshua and Still Alice by Lisa Genova as key texts, integrating real patient data and neurobehavioral assessments to construct a model that bridges clinical and literary approaches.
Study Design: This is a one-year prospective study.
Methods: Semi-structured interviews will be conducted to collect spontaneous narratives focusing on childhood memories, life events, and self-description. Audio recordings will be transcribed and analyzed for linguistic features and behaviors. In parallel, fictional narratives from selected dementia-themed novels will be analyzed for language disruption, narrative fragmentation, and identity construction in characters with dementia. A multidisciplinary team will conduct cross-comparative analyses between clinical data and literary texts to establish a reference framework of language decline and narrative behavior for future diagnostic support and empathy training.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosed with early-stage Alzheimer's disease or other mild cognitive impairment by a neurologist (case group) / healthy individuals matched for age and education level (control group)
- •Able to communicate and understand basic language
排除标准
- •Refuse to participate in the study
研究组 & 干预措施
Case group
Diagnosed with early-stage Alzheimer's disease or other mild cognitive impairment by a neurologist
Control group
Healthy individuals matched for age and education level
结局指标
主要结局
Mini-Mental State Examination
时间窗: on the day of enrollment
assess cognitive function, including orientation, memory, attention, language, and basic visuospatial ability
次要结局
未报告次要终点
研究者
Ke-Yun, Chao
Assistant Professor
Fu Jen Catholic University
