Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection (CRP-Track)

Not Applicable

Completed

• Conditions: Colorectal Postoperative Complication
• Interventions: Other: C-reactive protein dosage

• Registration Number: NCT02395380
• Lead Sponsor: Centre Hospitalier Departemental Vendee

Brief Summary

Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-03-02
• Study First Submitted QC: 2015-03-17
• Study First Posted: 2015-03-23
• Study Start: 2015-07-06
• Primary Completion: 2017-03-11
• Status Verified: 2017-06
• Study Completion: 2017-06-13
• Last Update Submitted: 2017-06-16
• Last Update Posted: 2017-06-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 176

Inclusion Criteria

• Upper age to 18 years
• Planned hospital stay for a colonic resection with anastomosis without permanent or temporary digestive bypass
• Patient with pre-operative CRP lower or egal to 172 mg/L
• No opposition at the participation of the study
• Expected patient return home after surgery (or convalescent home or not medicalized institution)

Exclusion Criteria

• Patient under guardianship
• Protected or private patient freedom
• Minor patient
• Colectomy surgery with digestive bypass or digestive anastomosis
• Complex combined surgery (significantly intestinal resection associated, another surgical procedure that can interfere with postoperative CRP)
• General inflammatory disease susceptive to modify dosage values
• Anti-inflammatory therapy (AINS/ corticosteroids/ immunosuppressive)
• Patient unable to understand the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
C-reactive protein dosage	C-reactive protein dosage	-

Primary Outcome Measures

Name	Time	Method
C-reactive protein rate	3 postoperative days	The time of postoperative recovery will be compared to the CRP values at 3 postoperative days.; The postoperative recovery is a composite endpoint defined by : * no pain \> 2 on the VAS scale; * presence of a gaseous bowel; * patient autonomy in terms of ambulation and body care (IRM 5-6); * no fever

Trial Locations

Locations (2)

Centre Hospitalier Departemental Vendee; 🇫🇷 La Roche sur Yon, France

CHU Nantes; 🇫🇷 Nantes, France