Muscle Function and Tenderness Differences in Headache Patients

• Conditions: Migraine; Tension Headache; Posttraumatic Headache

• Registration Number: NCT06859463
• Lead Sponsor: Danish Headache Center

Brief Summary

This cross-sectional study aims to compare muscle function of the neck, and shoulder and muscle tenderness in three groups of headache patients: migraine, tension-type headache, and posttraumatic headache. The study will evaluate muscle tenderness through the Total Tenderness Score (TTS) and muscle function through maximum voluntary isometric contraction (MVIC) and rate of force development (RFD). Additionally, functional assessments such as the Cranio-Cervical Flexion Test (CCFT) and Ito Test will be performed.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-02
• Study Start: 2025-02-28
• Study First Submitted: 2025-02-28
• Study First Submitted QC: 2025-02-28
• Study First Posted: 2025-03-05
• Last Update Submitted: 2025-03-05
• Last Update Posted: 2025-03-10
• Primary Completion: 2025-09-01
• Study Completion: 2026-03-01

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Criteria: Inclusion Criteria:

• Aged 18 to 65 years.
• Diagnosis of migraine, tension-type headache, or posttraumatic headache, occurring at least 10 days per month.
• For tension-type headache patients, maximum of 3 days per month with migraine.

Exclusion Criteria

• Pregnancy.
• Significant psychiatric comorbidities (e.g., severe depression).
• Medication-overuse headache.
• Severe osteoarthritis in the neck or shoulder, or cervical disc herniation.

Exclusion Criteria:

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary Outcome Measure: 1.Rate of Force Development (RFD)	1 year	Rate of Force Development (RFD) of the shoulder elevation Maximum voluntary isometric contraction performed "as fast and hard as possible" using a custom dynamometer for the shoulder elevation movement.

Trial Locations

Locations (1)

Danish Headache Center; 🇩🇰 Copenhagen, Region H, Denmark