Antibacterial effects of chlorhexidine , persica and saline mouthwashes

Not Applicable

• Conditions: Condition 1: ventilator associated pneumonia. Condition 2: ventilator associated pneumonia.; Pneumonia due to Streptococcus pneumoniae; Pneumonia due to staphylococcus

• Registration Number: IRCT138903254190N1
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Inclusion Criteria: Age between 15-65 years, Third and fourth day of admission in ICU, Intubation and mechanical ventilation for 3 to 4 days, having NG tube for 3 to 4

Exclusion Criteria

Re-intubation, History of antibiotic therapy before admission, Oral anticoagulation therapy,Respiratory and systemic infection, Autoimmune diseases and malignancies, History of allergy to mouthwash, asthma, allergic rhinitis and dermatitis, History of radiation therapy and immunosuppressive therapy including corticosteroid, Use of any kind of antimicrobial mouthwash within 2 months before admission, Diseases of oral mucosa and severe periodontitis, History of splenectomy and Tonsillectomy , Negative cultures of S.aureus and pneumoccocus before use of mouthwash, Occurrence of any reaction to Mouthwashes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of colony of S.aureus and pneumoccocus. Timepoint: Immediately before and after using mouthwashes. Method of measurement: CFU(Colony-forming unit).

Secondary Outcome Measures

Name	Time	Method
Any reaction to Mouthwashes. Timepoint: after using of mouthwashes. Method of measurement: inspection.