Evoked Potentials after Painful Cutaneous Electrical Stimulation Depict Pain Relief during a Conditioned Pain Modulatio

• Conditions: Healthy volunteers

• Registration Number: DRKS00012779
• Lead Sponsor: Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-01-01
• Study Start: 2017-07-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Healthy subjects, age>18 years, given written informed consent

Exclusion Criteria

Current pain, neuropathy, nerve lesions, topical drug treatment, history of neurological, psychiatric or severe cardiovascular diseases

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome of this trial is the reduction of PCES-EP induced by painful cold water. Therefore, we assessed the ratio of the amplitude of PCES-EP before and during conditioning cold water.

Secondary Outcome Measures

Name	Time	Method
As secondary outcome parameter, we assessed the relief of PCES induced pain using a 101-point numerical rating scale before and during conditioning cold water as a ratio.