Effects of Vitamin D Supplements on Pregnancy Outcomes in Embriyo Transfer Cycles
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 118
- 试验地点
- 1
- 主要终点
- Blood Vitamin D level
研究概览
简要总结
Objective: To examine the effect of vitamin D supplements on the pregnancy and clinical pregnancy rate in embryo transfer cycles.
Design: Experimental study with a pre- and post-test. Setting: In Vitro Fertilization Center Patients: Its sample consisted of 118 women, 58 in the experimental group and 60 in the control group.
Intervention(s): At the beginning of the infertility treatment, the experimental group took vitamin D supplements, and the control group did not. Vitamin D supplementation for infertile women includes regulation of a diet rich in vitamin D, educational and motivational interviews about insolation, and taking vitamin D orally.
Main Outcome Measure(s): 25(OH)D and beta HCG levels
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •18-45 years old
- •literate in Turkish
- •voluntary participation
- •primarily infertile
- •had undergone controlled ovarian hyperstimulation and had a fresh ET
- •vitamin D levels lower than 30ng/mL before infertility treatment
排除标准
- •patients with uncorrected congenital or acquired uterine anomalies
- •bone, parathyroid gland, kidney and liver disorders
- •use of anticonvulsants/antacid drugs
- •taking dietary supplements contain vitamin D
- •secondary infertility
研究组 & 干预措施
Experimental
干预措施: DEVIT-3 (Drug)
结局指标
主要结局
Blood Vitamin D level
时间窗: The 25 (OH)D levels of the women were tested on the two weeks after embryo transfer. (Posttest)
The vitamin D blood test was measured by the level of 25(OH)D.
次要结局
- Biochemical pregnancy(HCG levels of the women were evaluated on the two weeks after embryo transfer (Post test))