Glucose Metabolism After Partial Pancreatectomy
Completed
- Conditions
- Pancreatectomy; HyperglycemiaDiabete Mellitus
- Interventions
- Diagnostic Test: oral glucose tolerance test
- Registration Number
- NCT04409171
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Detailed Description
Biochemical markers of glucose metabolism including oral glucose tolerance tests, fasting blood glucose, insulin, glucagon and HbA1c were performed on patients receiving pancreatectomy (pancreaticoduodenectomy and distal pancreatectomy). Tests were done preoperatively, postoperatively at 3 months, and at 1 year. The primary endpoints were the incidence and risk factors of new-onset and worsened DM after each type of pancreatectomy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 224
Inclusion Criteria
- partial pancreatectomy
Exclusion Criteria
- total pancreatectomy
- incomplete testing
- follow-up loss
- death within 1 year
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description PD oral glucose tolerance test pancreaticoduodenectomy DP oral glucose tolerance test distal pancreatectomy
- Primary Outcome Measures
Name Time Method incidence & risk factors of new-onset DM at 1 year incidence \& risk factors of new onset DM after pancreatectomy
incidence & risk factors of worsened DM at 1 year incidence \& risk factors of worsened DM after pancreatectomy
- Secondary Outcome Measures
Name Time Method characteristics of new-onset and worsened DM 1 year changes of glucose metabolism during study period