Alteration of Glucose Metabolism After Partial Pancreatectomy Assessed With Biochemical Markers :A Single Center Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 224
- 主要终点
- incidence & risk factors of new-onset DM
研究概览
简要总结
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
详细描述
Biochemical markers of glucose metabolism including oral glucose tolerance tests, fasting blood glucose, insulin, glucagon and HbA1c were performed on patients receiving pancreatectomy (pancreaticoduodenectomy and distal pancreatectomy). Tests were done preoperatively, postoperatively at 3 months, and at 1 year. The primary endpoints were the incidence and risk factors of new-onset and worsened DM after each type of pancreatectomy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •partial pancreatectomy
排除标准
- •total pancreatectomy
- •incomplete testing
- •follow-up loss
- •death within 1 year
结局指标
主要结局
incidence & risk factors of new-onset DM
时间窗: at 1 year
incidence \& risk factors of new onset DM after pancreatectomy
incidence & risk factors of worsened DM
时间窗: at 1 year
incidence \& risk factors of worsened DM after pancreatectomy
次要结局
- characteristics of new-onset and worsened DM(1 year)
研究者
Yoo-Seok Yoon
Associate Professor
Seoul National University Bundang Hospital