EXPLORATORY RESEARCH FOR CONSTRUCTION AND APPLICATION OF A DATABASE OF THE NORMAL GABAA RECEPTOR BRAIN SPECT TO VISUALIZE NEURONAL LOSS IN NEURODEGENERATIVE DISEASES

Not Applicable

Recruiting

• Conditions: neurodegenerative diseases such as amyotrophic lateral sclerosis

• Registration Number: JPRN-UMIN000028088
• Lead Sponsor: Department of Neurology, Niigata National Hospital, National Hospital Organization

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-07-05
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 13

Inclusion Criteria

Not provided

Exclusion Criteria

[Normaldatabase creation] 1) Subject is a pregnant, is capable of being pregnant, or is breast-feeding 2) Subject has a history of alcohol poisoning or is receiving treatment for it 3) SUbject has a history of epilepsy or is receiving treatment for it 4) Subject is receiving antidepressants, psychotropics, prolonged hypnotic sedatives (including anxiolytics) 5) Subject has a history of mental/neurological diseases that affect cognitive function 6) Subject has a serious complications (liver, kidney disorders and endocrine diseases etc.) 7) Smoker (more than 20 years having one-packet and more per day) [Assessment of lesional distribution] 1) ubject is a pregnant, is capable of being pregnant, or is breast-feeding 2) Subject has a serious complications (liver, kidney disorders and endocrine diseases etc.)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Projection data of IMZ SPECT

Secondary Outcome Measures

Name	Time	Method
Head MRI(T1,T2,FLAIR,sDWI,T2*,3D-T1,MRA)