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临床试验/CTRI/2024/08/072817
CTRI/2024/08/072817尚未招募不适用

Incidence and predictors of unanticipated difficult airway in cases of ankylosing spondylitis – a prospective observation single centric study

Abin Iype1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年8月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
incidence of situations of unanticipated difficult airway among cases of ankylosing

研究概览

简要总结

American society of anesthesiologists defines a difficult airway as the clinical situation in which a

trained anesthesiologist has difficulty with face mask ventilation of the upper airway, difficulty with

tracheal intubation, or both. Ankylosing spondylitis (AS) can present significant challenges to the

anesthetist in view of potentially difficult airway with worsening disease status, namely limitation of

movement at the cervical spine and jaw. Associated systemic factors such as pulmonary and cardiovascular

complications, along with the risk of iatrogenic cervical spine fractures leading to neurological

deterioration adds on to the challenge. However, a careful pre-operative assessment of the overall

functional status of the patient along with a comprehensive airway assessment will allow the

anesthetist to anticipate and circumvent problems faced intra-operatively, thereby reducing overall

morbidity and mortality associated with anesthesia. This study aims to identify systemic and airway

parameters associated with the disease that could serve as predictors of an unanticipated difficult

airway

研究设计

研究类型
Observational

入排标准

年龄范围
15.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Patients presenting at any age, with more than 3-month history of back pain, and a documented positive testing for human leucocyte antigen B27, posted for elective surgery requiring general anesthesia with endotracheal intubation.

排除标准

  • Acute or chronic mechanical non-specific back pain and inflammatory back pain without Spondylarthritis, including disc disease and discogenic pain syndrome, facet syndrome, radiculopathy, acute bony injuries, spondylolisthesis, spondylosis, SI joint injuries and lumbar canal stenosis, fibromyalgia, vertebral compression, or insufficiency related fractures.
  • Other factors causing anticipated difficult airway, such as obvious airway malformations, oral masses, unstable cervical spine, and others requiring emergent surgeries.

结局指标

主要结局

incidence of situations of unanticipated difficult airway among cases of ankylosing

时间窗: In the theatre, on the day of planned elective surgery, during the induction of general anesthesia and subsequent intubation. No follow-up required.

spondylitis.

时间窗: In the theatre, on the day of planned elective surgery, during the induction of general anesthesia and subsequent intubation. No follow-up required.

次要结局

未报告次要终点

研究者

发起方
Abin Iype
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Abin Iype

Christian Medical College And Hospital, Vellore

研究点 (1)

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