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Clinical Trials/NCT06230796
NCT06230796
Recruiting
Not Applicable

Effects of FES-cycling in Patients With Hemiparesis After Stroke

UGECAM Rhône-Alpes1 site in 1 country30 target enrollmentNovember 17, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hemiparesis;Poststroke/CVA
Sponsor
UGECAM Rhône-Alpes
Enrollment
30
Locations
1
Primary Endpoint
VO2 peak at 2 months (L/min)
Status
Recruiting
Last Updated
7 months ago

Overview

Brief Summary

To determine whether active cycling assisted by functional electrical stimulation (FES) Is more effective than active cycling on cardiovascular fitness in post stroke hemiparesis

Detailed Description

Design: In a monocentric, single-blind, randomized, controlled trial, hemiparetic post stroke patients will be randomized to receive FES-induced cycling training or placebo FES cycling. Setting: Neurologic Rehabilitation Unit Interventions: 30 minutes of active leg cycling with or without FES applied to the paretic rectus femoris of quadriceps and to the biceps femoris and semitendinosus muscles and gluteus maximus, 3 times/weeks for 8 weeks. During training, participants will be seated on a FES-Cycle (Hepha Bike, Kurage): a cyclo-ergometer (Technogym) combined with a 8 channel controlled stimulator (Motimove-8). In addition to the assigned group treatment, subjects will perform their own standard rehabilitation program. Participants will be evaluated before training, after training, and at 3 month follow-up visit

Registry
clinicaltrials.gov
Start Date
November 17, 2023
End Date
December 1, 2025
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
UGECAM Rhône-Alpes
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adults with Hemiparesis after an unilateral first ever stroke
  • Able to walk in security
  • Time since stroke within 3 months to 1 year
  • Sufficient cognitive function to understand and perform corresponding tasks

Exclusion Criteria

  • Any history of neurological disorders or cardiovascular instability
  • High spasticity on ankle, knee, hip muscles
  • Inability to exercise on a cyclo-ergometer
  • Pacemaker and other contraindications of the use of electrical stimulation

Outcomes

Primary Outcomes

VO2 peak at 2 months (L/min)

Time Frame: From enrollment to the end of treatment at 8 weeks

Comparison of the maximum oxygen consumption (VO2 peak in L/min) measured during an incremental maximum stress test on cyclo-ergometer between the end of training (M2) and inclusion (M0).

Secondary Outcomes

  • Cognitive function(2 months)
  • Maximum power(2 months)
  • Walking ability(4 months)
  • quadriceps muscular thickness(2 months)
  • Middle Cerebral Artery Blood Flow Velocity During Exercise(2 months)

Study Sites (1)

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