MedPath

ltrafiltration effect on coronary artery bypass surgery

Phase 2
Conditions
Coronary Artery Disease.
Atherosclerotic cardiovascular disease, so described
Registration Number
IRCT2016092229914N1
Lead Sponsor
Vice CHancellor For Research, Iran university Of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
75
Inclusion Criteria

Non-inclusion criteria
Liver failure as ((AST> 40 unit / L) and (ALT> 40 unit / L);A history of heart surgery;High serum creatinine1/5mg / dL; And patients who received the drug because before during 5 days acute renal failure have had severe narrowing of the carotid both carotid or one of them; Surgery emergency; IE; Ejection fraction of the left ventricle less than 30 percent of patients with Severe failure right ventricle Hemoglobin less than 10;Mass index BMI greater than 40;Benign and malignant cancers;Clamped aortic bypass for more than 120 minutes and 150 minutes; Pulmonary function test abnormal preoperative FEV1 <65

Exclusion criteria
Prime 8/5000
Autologus do the opposite; Using the CUF; Using MUF; Patient died during surgery; Use of Intraoperative balloon pump;Use of ECMO; The need to stay open sternum after surgery; The patient needs cardiopulmonary resuscitation

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cerebral oxygenation. Timepoint: 1.Preoperative2.Start operation3.Intraoperative4.Postoperative2. Method of measurement: Invos devices.;Arterial blood gases. Timepoint: Before surgery2.Start operation3.Intraoperative4.End the practice of5.6 hours after surgery. Method of measurement: Arterial blood gas measurement.;Liver enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory.;Kidney enzymes. Timepoint: Preoperative and postoperative. Method of measurement: Measured by laboratory.;Cardiac arrhythmia. Timepoint: Preoperative and postoperative. Method of measurement: ECG machine.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath