CTRI/2025/04/084571尚未招募4 期
To Compare the Efficacy of Intravenous Ibuprofen Vs Intravenous Paracetamol as Post Operative Analgesia in Patients Undergoing Abdominal Hysterectomy
Dr Sangeetha Arunachalam1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2025年5月15日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- To compare the analgesic effect of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesia in patients who have undergone abdominal hysterectomy.
研究概览
简要总结
It is a prospective, randomized, double blinded comparative study to compare the analgesic efficacy of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesics in patients who have undergone abdominal hysterectomy.
Parameters that will be compared between the two groups will be the efficacy, duration of analgesia and time to rescue analgesia between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Female
入选标准
- •ASA grade 1 or 2 fit patients.
- •Patients undergoing abdominal hysterectomy.
- •Haemodynamically stable patients with all investigations within normal limits.
- •Written informed consents from concerned patients.
排除标准
- •Patients not willing to participate in study
- •Patients with ASA grade 3 and above
- •Patients aged less than 30 and more than 60 years.
- •Patients posted for emergency procedures.
- •Patients with difficult intubation.
- •Patients with psychiatric conditions, coagulopathies, naurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.
- •Patients with coagulopathies and contraindications to spinal anaesthesia.
结局指标
主要结局
To compare the analgesic effect of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesia in patients who have undergone abdominal hysterectomy.
时间窗: After administration of intravenous analgesic, comparison between 2 groups of efficacy and duration of action by monitoring VAS scores at 0,2,4,6,8,12,24,48 hours respectively.
次要结局
- To compare the analgesic effect of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesia in patients who have undergone abdominal hysterectomy.(At baseline, 2 hrs, 4 hrs, 6 hrs, 8 hrs, 12 hrs, 24 hrs & 48 hrs after administration of medication)
研究者
研究点 (1)
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