Measurement of the sublingual microcirculation in critically ill children at the bedside: a pilot study

Completed

• Conditions: microcirculatie; microcirculation

• Registration Number: NL-OMON55784
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

-mechanically ventilation for at least 24 hours
-sedation
-0-18 years

Exclusion Criteria

-no written informed consent from both parents

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter is to determine the within-patient reproducibility<br /><br>of the sequential measurement of the microcirculatory region of interest in<br /><br>critically ill children. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The second aim is to design a more practical way to analyze and interpret the<br /><br>microcirculatory bedside derived datasets. Sublingual microcirculatory<br /><br>measurements will be evaluated with a CytoCam, an optical spectroscopic<br /><br>sensor-based digital video imaging instrument (Braedius Medical BV, The<br /><br>Netherlands). Sublingual microcirculation profile consists of blood vessel<br /><br>diameter (BVd), proportion of perfused vessels (PVV), perfused vessel density<br /><br>(PVD), microcirculatory flow index (MFI) and total vascular density (TVD).</p><br>