Sublingual microcirculatory flow measurements during haemodialysis in relation to blood volume change

Completed

• Conditions: dialyse en microcirculatie; haemodialysis and microcirculation

• Registration Number: NL-OMON35974
• Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

informed consent
age > 18
haemodialysis patient

Exclusion Criteria

instabil haemodynamics
oral surgery

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoints:<br /><br>1. difference between sublingual MFI at the end of hemodialysis without<br /><br>ultrafiltration (b) and the end of hemodialysis with ultrafiltration (a)<br /><br>2. difference in sublingual MFI at the end of two ultrafiltration methods<br /><br>(standard (a) versus BVM (c)). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints:<br /><br>1. difference in sublingual MFI time points t = 1 and t = 2 hours for 3<br /><br>sessions (a vs b and a vs. c).<br /><br>2. difference in change in MFI from baseline at t = 1, t = 2 and t = 4 hours<br /><br>for 3 sessions (a vs b and a vs. c).<br /><br>3. correlation between the change of MFI at the end of the session parameters<br /><br>and ultrafiltration volume, ultrafiltration rate, blood pressure, pulse, dry<br /><br>mass (BCM) and laboratory parameters. </p><br>