Prevalence of Microcirculatory Alterations in Intensive Care Patients
- Conditions
- Critical Illness
- Registration Number
- NCT01179243
- Lead Sponsor
- Medical Centre Leeuwarden
- Brief Summary
Recent research has focused on the investigation of sublingual microcirculatory alterations in different patient categories, like cardiac surgery and sepsis. The microcirculation plays a pivotal role in tissue oxygenation and can be non invasively visualized by sidestream dark field (SDF) imaging.
The objective is to carry out a international multi center study to investigate the prevalence of microcirculatory alterations in intensive care patients. Up to the present time, a comprehensive prevalence study like this has not been carried out.
- Detailed Description
Visualization of the sublingual microcirculation at a fixed time point with SDF- or OPS-imaging in all adult patients of participating intensive care units, regardless of their underlying disease. Concurrently, data on both patient characteristics (e.g. severity of illness, treatment) and ICU characteristics will be obtained.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 500
- > 18
- informed consent
- injury to the maxillofacial area
- recent maxillofacial injury
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method microcirculatory alterations related to underlying illness, expressed as - amongst others- microvascular flow index (MFI), proportion of perfused vessels (PPV). 24 hours
- Secondary Outcome Measures
Name Time Method microcirculatory alterations related to: hospital/intensive care length of stay mortality severity of illness 28 days
Trial Locations
- Locations (4)
Medical Centre Leeuwarden
🇳🇱Leeuwarden, Netherlands
Erasmus MC Rotterdam
🇳🇱Rotterdam, Netherlands
OLVG
🇳🇱Amsterdam, Netherlands
Gelre Ziekenhuis Apeldoorn
🇳🇱Apeldoorn, Netherlands