MedPath

Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis

Completed
Conditions
Chronic Bronchitis
COPD
Registration Number
NCT00454675
Lead Sponsor
Westside Family Medical Center, P.C.
Brief Summary

To determine whether an average population of males and females who smoke 10 pack years or more of cigarettes in a primary care setting with chronic bronchitis has already developed significant changes on pulmonary function testing.

Detailed Description

The incident of COPD is dramatically increasing while other chronic disease states are decreasing in the US population. Smoking cigarettes is the leading risk factor for COPD. Smokers with chronic bronchitis may show early or late changes of COPD on pulmonary function tests. It is imperative that we define this patient population to determine whether early intervention will alter pulmonary function over the years.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100
Inclusion Criteria
  1. Subjects must sign a written informed consent.
  2. Enrollment population would include males and females 40 years of age to 80 years of age.
  3. Current history or past history of smoking at least 10 pack years of cigarettes.
  4. Patients to satisfy the diagnosis of chronic bronchitis.
  5. Non-smokers will be allowed in the control group
Exclusion Criteria
  1. Chronic infections such as TB or other infections of the lungs.
  2. Collagen diseases such as rheumatoid arthritis or lupus which affect the lungs.
  3. Any previous lung diseases such as pneumoconiosis.
  4. Previous accidents or surgery which would involve the lungs or the ribcage.
  5. Maintenance medications used for asthma or COPD such as long acting bronchodilators or inhaled corticosteroids.
  6. Asthma patients or other patients with allergies that may affect pulmonary function test will be excluded.
  7. Any medical condition in the opinion of the investigator that would make the subject unsuitable for enrollment.
  8. Pregnant woman will not be allowed
  9. Current participation in a research study or within the last 30 days.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Westside Family Medical Center, P.C.

🇺🇸

Kalamazoo, Michigan, United States

Westside Family Medical Center, P.C.
🇺🇸Kalamazoo, Michigan, United States

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