Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis
Not Applicable
Withdrawn
- Conditions
- Renal FailureMulti Organ Failure
- Registration Number
- NCT00752245
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with sepsis/multi-organ failure. The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- ICU patients with sepsis/multi-organ failure with acute renal failure
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Registration of toxin removal efficiency During dialysis
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link uremic toxins to sepsis-induced acute kidney injury?
How does extended dialysis duration (8h) compare to standard (4h) in clearing uremic toxins in ICU patients with sepsis?
Which biomarkers correlate with uremic toxin clearance rates in septic acute renal failure patients?
What are the potential adverse events associated with prolonged dialysis in multi-organ failure patients?
Are there combination therapies with dialysis that improve outcomes for sepsis-related acute kidney injury?
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium
University Hospital Ghent🇧🇪Ghent, Belgium