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Clinical Trials/NCT06076395
NCT06076395
Active, not recruiting
Not Applicable

The Effect of Volume Controlled Versus Pressure Ventilation on Anesthesia Induced Lung Atelectasis in Pediatrics Using Laryngeal Mask Airway (LMA )During Cardiac Catheterization. A Prospective Randomized Study.

Kasr El Aini Hospital1 site in 1 country60 target enrollmentJanuary 12, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiac Congenital Defects
Sponsor
Kasr El Aini Hospital
Enrollment
60
Locations
1
Primary Endpoint
Post operative incidence of Lung atelectasis immediate post-removal of LMA.
Status
Active, not recruiting
Last Updated
2 years ago

Overview

Brief Summary

This prospective randomized comparative study, to assess post-operative lung atelectasis by comparing calculated lung score using ultrasound between pediatric patients intubated with LMA (laryngeal mask airway) under volume versus pressure controlled modes of ventilation.

Detailed Description

The initial US scanning will be done prior to the induction of anesthesia. Induction of anesthesia using 4% sevoflurane. Adequate size LMA will be inserted after adequate depth of anesthesia adjusted. Group A (n=25): will receive pressure-controlled ventilation (PCV). Group B (n=25): will receive volume-controlled ventilation (VCV). US scanning and Arterial blood gases at the following: * T1(After maintenance of anesthesia). * T2 (One minute after applying groin bandage and before extubation). * T3 (10 minutes after extubation and resumption of adequate regular breathing). * T4 (30 min post extubation).

Registry
clinicaltrials.gov
Start Date
January 12, 2024
End Date
August 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kasr El Aini Hospital
Responsible Party
Principal Investigator
Principal Investigator

Dalia Saad Abd-El Kader

assistant professor

Kasr El Aini Hospital

Eligibility Criteria

Inclusion Criteria

  • Pediatric patients undergoing cardiac catheterization procedures. Age from 2 years to 6 years of both sexes.

Exclusion Criteria

  • Lung score at different times.
  • Age \<2 years and \>6 years.
  • Preoperative mechanical ventilation.
  • Heart failure (any inotropic support infusion).
  • Patients with any lung diseases( acute respiratory disease, pulmonary or lung
  • diseases).
  • Lung consolidation score ≥ 2 before insertion of LMA.
  • Any contraindication for LMA insertion (risk for aspiration, and/or airway
  • obstruction below the larynx.)
  • Procedures exceeding 120 mins duration.

Outcomes

Primary Outcomes

Post operative incidence of Lung atelectasis immediate post-removal of LMA.

Time Frame: immediated post removal of LMA

calculate lung score using lung ultrasound

Secondary Outcomes

  • Correlation between lung score and PaO2 /FiO2 ratio(From the preoperative period (T0) to 30 minutes post-extubation)

Study Sites (1)

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