Effects of Pneumoperitoneum on Ventilatory Parameters in Patients Undergoing Video-assisted Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Surgery--Complications
- Sponsor
- Institutul Clinic Fundeni
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- lung compliance
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery.
The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion
Investigators
Popescu Mihai
Clinical Professor
Institutul Clinic Fundeni
Eligibility Criteria
Inclusion Criteria
- •patients who underwent video-assisted surgery by either classic laparoscopy or robotic-assisted surgery.
Exclusion Criteria
- •refusal to participate
- •conversion of surgery to laparotomy
- •need of vasopressure support
- •preoperative severe respiratory dysfunction
Outcomes
Primary Outcomes
lung compliance
Time Frame: one-hour and two-hours after induction of pneumoperitoneum
change in lung compliance (mL/cmH2O) before and after induction of pneumoperitoneum in patients undergoing VAS. Lung compliance is automatically calculated by the anesthesia machine during surgery. The study compares the magnitude in change associated with VAS.
Secondary Outcomes
- arterial to end-tidal CO2 difference(one-hour and two-hours after induction of pneumoperitoneum)