Effects of Pneumoperitoneum on Ventilatory Parameters in Patients Undergoing Video-assisted Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- lung compliance
研究概览
简要总结
The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery.
The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who underwent video-assisted surgery by either classic laparoscopy or robotic-assisted surgery.
排除标准
- •refusal to participate
- •conversion of surgery to laparotomy
- •need of vasopressure support
- •preoperative severe respiratory dysfunction
结局指标
主要结局
lung compliance
时间窗: one-hour and two-hours after induction of pneumoperitoneum
change in lung compliance (mL/cmH2O) before and after induction of pneumoperitoneum in patients undergoing VAS. Lung compliance is automatically calculated by the anesthesia machine during surgery. The study compares the magnitude in change associated with VAS.
次要结局
- arterial to end-tidal CO2 difference(one-hour and two-hours after induction of pneumoperitoneum)
研究者
Popescu Mihai
Clinical Professor
Institutul Clinic Fundeni