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Clinical Trials/NCT02709252
NCT02709252
Completed
Phase 2

Effect of the Pneumoperitoneum on Dynamic Variables Delta PP and PVI During Trendelenburg Position.

Brugmann University Hospital1 site in 1 country50 target enrollmentJanuary 2011
ConditionsSurgery

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Surgery
Sponsor
Brugmann University Hospital
Enrollment
50
Locations
1
Primary Endpoint
Pulse Pressure variation (deltaPP) (in %)
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Arterial pulse pressure variation induced by mechanical ventilation (ΔPP) is considered one of the best parameter to predict fluid responsiveness in patients under general anaesthesia. Pleth Variability Index (PVI) has been proposed as a less invasive alternative. However, the pneumoperitoneum has been recently seen suggested as a limitation to their interpretation. The aim of this observational study is to compare changes in ΔPP and PVI related to autotransfusion associated with a Trendelenburg manoeuver before and during laparoscopy in patients undergoing elective surgery.

Registry
clinicaltrials.gov
Start Date
January 2011
End Date
December 2013
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Forget Patrice

PI

Université Catholique de Louvain

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Pulse Pressure variation (deltaPP) (in %)

Time Frame: 5 minutes

Before/after trendelenburg positioning in laparoscopic surgery

Pleth variability index (in %)

Time Frame: 5 minutes

Before/after trendelenburg positioning in laparoscopic surgery

Study Sites (1)

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