Analgesic effect of intravenous magnesium sulfate during bimaxillary orthognatic surgery
Phase 2
- Conditions
- Bimaxillary Orthognathic Surgery.00
- Registration Number
- IRCT201307101674N7
- Lead Sponsor
- Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Patients with no history of systemic disease and without taking any analgesic medications criteria that were willing to cooperate in this study were enrolled; and Exclusion criteria included known allergy to the study drugs; hepatic and renal dysfunction ; patients with heart block or myocardial damage; morbid obesity (BMI = 35); neuromuscular disease; history of neuropathy; asthma; Use of opioid or analgesics 3 days before the study; use of calcium channel blockers and Patients who did not sign the informed consent.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The intensity of the pain. Timepoint: Every half hour for twelve hours after operation. Method of measurement: Visual analog scale.;Heart rate and blood pressure. Timepoint: Before, during and after surgery. Method of measurement: ECG and blood pressure monitoring device.;Duration of surgery. Timepoint: End of surgery. Method of measurement: The Minutes.
- Secondary Outcome Measures
Name Time Method The use of sedative or narcotic. Timepoint: In the recovery room and surgical ward. Method of measurement: Visual analog scale.;Magnesium Sulfate side effects. Timepoint: Postoperative and in the ward Surgery. Method of measurement: Questionnaire.;Urine volume. Timepoint: From beginning to end the operation. Method of measurement: cc/kg/min.