HIV Patients Cohort

Not Applicable

Active, not recruiting

• Conditions: Patients Affected by the HIV
• Interventions: Biological: OVIHD

• Registration Number: NCT02203006
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The purpose of this study is to improve our knowledge concerning HIV infection, treated or not, in the current conditions of care to optimize it.

Detailed Description

Since the arrival of highly active tritherapies, HIV infection became mainly an ambulatory chronic pathology centred on a long term care taking into account the complication of long-term treatment as well as the arisen of new problem bound to a prolonged survival and ageing. So the care is more and more in a prevention and screening approach with in particular the care of metabolic and cardiovascular complication due to antiretroviral treatment.

As a reorganization of the coverage of the HIV infected people take place on the Hotel Dieu Hospital it thus seems important to double this care optimization with a clinical research side. This will be done in constituting an HIV patient cohort including a blood sample collection to contribute to the vigilance of the complication to due the infection.

Our ultimate objective is to optimize the selection of the treatment. It is important to do it to be able to have, on many years duration, precise clinical information and biological sample allowing to realize later some assay and analyse the influence of some genetic markers.

Study Timeline

• Study Start: 2011-10-19
• Study First Submitted: 2014-07-25
• Study First Submitted QC: 2014-07-25
• Study First Posted: 2014-07-29
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-28
• Last Update Posted: 2022-10-31
• Primary Completion: 2030-10
• Study Completion: 2031-04

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1613

Inclusion Criteria

• Aged ≥18 years old,
• Patients with an HIV infection
• patients having given their written informed consent.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
OVIHD	OVIHD	Cohort and a blood sample collection will be done with data and blood of HIV infected patients

Primary Outcome Measures

Name	Time	Method
HIV infection	10 years	The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient)

Secondary Outcome Measures

Name	Time	Method
Comorbidity and complication in HIV infected patients	10 years	The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient)
efficiency of the current antiretroviral therapeutic diets	10 years	The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient)
Blood sample collection	10 years	To put in relation the clinical-biological relevant biological or genetic data of the follow-up a blood sample will be constituted. 7 ml will be taken to each patient and kept in a collection

Trial Locations

Locations (1)

Hôpital Hôtel Dieu; 🇫🇷 Paris, France